5.5.1. What is the difference between pre- and post-exposure prophylaxis?

 PreP [1] is given prior to an exposure and does not include RIG [2]. It is given to those at highest risk of being exposed, for example people working in a rabies vaccine manufacturing facility or in a rabies diagnostic laboratory, veterinarians, and those living in or traveling to regions of the world where rabies is highly endemic or currently epidemic, especially children living at daily risk of exposure.
 PEP [3]is given after an exposure to rabies has occurred and should include both RIG and rabies vaccine.
 A person that has received either PreP or PEP previously and is subsequently exposed to rabies does not need to receive RIG, and only needs two booster doses of vaccine, one given on day 0 and one on day 3.